caption a7 time kill curves for mssa (ATCC)
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Caption A7 Time Kill Curves For Mssa, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 297 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Article Title: In Vitro Activity of TD-6424 against Staphylococcus aureus
Journal:
doi: 10.1128/AAC.47.11.3602-3604.2003
Figure Legend Snippet: In vitro activities of TD-6424 and comparator antibiotics against MRSA and MSSA
Techniques Used: In Vitro
Figure Legend Snippet: Time-kill curves for MSSA (ATCC 13709) (A), MRSA (ATCC 33591) (B), and GISA (HIP 5836) (C). (A) Vancomycin at 4 times the MIC (⧫), nafcillin at 4 times the MIC (▪), linezolid at 4 times the MIC (▴), and TD-6424 at 4 times the MIC (▵); (B) vancomycin at 8 times the MIC (⧫), linezolid at 8 times the MIC (▴), and TD-6424 at 8 (▵) and 32 (▪) times the MIC; (C) linezolid at 4 times the MIC (▴), vancomycin at 4 times the MIC (⧫), and TD-6424 at 4 (▵), 8 (▪), and 16 (□) times the MIC. ✻, bacterial growth control. The nafcillin MIC was 1 μg/ml for ATCC 13709. Vancomycin MICs were 1, 1, and 8 μg/ml for ATCC 13709, ATCC 33591, and HIP 5836, respectively; the corresponding values were 2, 2, and 2 μg/ml for linezolid and 1, 1, and 2 μg/ml for TD-6424.
Techniques Used: Control
Figure Legend Snippet: PAE for TD-6424 and comparator antibiotics
Techniques Used:
Related Articles
In Vitro:Article Title: In Vitro Activity of TD-6424 against Staphylococcus aureus Article Snippet: By 4 h, the 8- and 32-μg/ml concentrations had reduced the initial inoculum from log 10 5.76 ± 0.07 to 3.21 ± 0.12 and 0.98 ± 0.02 CFU/ml, respectively.. Linezolid at 8 μg/ml reduced the initial inoculum from log 10 5.76 ± 0.07 CFU/ml to log 10 2.73 ± 0.08 CFU/ml by 4 h, and vancomycin at 32 μg/ml decreased it from log 10 5.76 ± 0.07 CFU/ml to log 10 4.82 ± 0.02 CFU/ml over this period. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 1. caption a7 Time-kill curves for MSSA ( Control:Article Title: In Vitro Activity of TD-6424 against Staphylococcus aureus Article Snippet: By 4 h, the 8- and 32-μg/ml concentrations had reduced the initial inoculum from log 10 5.76 ± 0.07 to 3.21 ± 0.12 and 0.98 ± 0.02 CFU/ml, respectively.. Linezolid at 8 μg/ml reduced the initial inoculum from log 10 5.76 ± 0.07 CFU/ml to log 10 2.73 ± 0.08 CFU/ml by 4 h, and vancomycin at 32 μg/ml decreased it from log 10 5.76 ± 0.07 CFU/ml to log 10 4.82 ± 0.02 CFU/ml over this period. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window FIG. 1. caption a7 Time-kill curves for MSSA ( |